Literature summary for 6.3.2.2 extracted from

Botta, D.; Shi, S.; White, C.C.; Dabrowski, M.J.; Keener, C.L.; Srinouanprachanh, S.L.; Farin, F.M.; Ware, C.B.; Ladiges, W.C.; Pierce, R.H.; Fausto, N.; Kavanagh, T.J.
Acetaminophen-induced liver injury is attenuated in male glutamate-cysteine ligase transgenic mice (2006), J. Biol. Chem., 281, 28865-28875.

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Cloned(Commentary)

Cloned (Comment)	Organism
generation of C57Bl/6 mice that conditionally overexpress glutamate-cysteine ligase	Mus musculus

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
liver	male transgenic mice induced to overexpress glutamate-cysteine ligase exhibit resistance to acetaminophen-induced liver injury when compared with acetaminophen-treated male mice carrying, but not expressing glutamate-cysteine ligase transgenes, or to female glutamatecysteine ligase transgenic mice	Mus musculus	-

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Release 2023.1 (January 2023)