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Literature summary for 6.3.2.2 extracted from

  • Dasgupta, A.; Das, S.; Sarkar, P.K.
    Thyroid hormone promotes glutathione synthesis in astrocytes by up regulation of glutamate cysteine ligase through differential stimulation of its catalytic and modulator subunit mRNAs (2007), Free Radic. Biol. Med., 42, 617-626.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
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Source Tissue

Source Tissue Comment Organism Textmining
astrocyte
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Rattus norvegicus
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telencephalon
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Rattus norvegicus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-glutamate + L-cysteine thyroid hormone promotes glutathione synthesis in astrocytes by upregulation of glutamate cysteine ligase through differential stimulation of its catalytic and modulator subunit mRNAs Rattus norvegicus ADP + phosphate + gamma-L-glutamyl-L-cysteine
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