Literature summary for 6.3.2.12 extracted from

Hauser, P.M.; Macreadie, I.G.
Isolation of the Pneumocystis carinii dihydrofolate synthase gene and functional complementation in Saccharomyces cerevisiae (2006), FEMS Microbiol. Lett., 256, 244-250.

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Cloned(Commentary)

Cloned (Comment)	Organism
Pneumocystis carinii DHFS expressed from a plasmid functionally complements a Saccharomyces cerevisiae mutant with no DHFS	Pneumocystis carinii

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + 7,8-dihydropteroate + L-glutamate	Pneumocystis carinii	the enzyme is involved in the essential biosynthesis of folates	ADP + phosphate + 7,8-dihydropteroylglutamate	-	?

Organism

Organism	UniProt	Comment	Textmining
Pneumocystis carinii	Q2VIK1	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + 7,8-dihydropteroate + L-glutamate	the enzyme is involved in the essential biosynthesis of folates	Pneumocystis carinii	ADP + phosphate + 7,8-dihydropteroylglutamate	-	?

Synonyms

Synonyms	Comment	Organism
DHFS	-	Pneumocystis carinii

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Release 2023.1 (January 2023)