BRENDA - Enzyme Database
show all sequences of 6.3.2.10

Nucleotide sequence of the murF gene encoding the UDP-MurNAc-pentapeptide synthetase of Escherichia coli

Parquet, C.; Flouret, B.; Mengin-Lecreulx, D.; van Heijenoort, J.; Nucleic Acids Res. 17, 5379 (1989)

Data extracted from this reference:

Organism
Organism
UniProt
Commentary
Textmining
Escherichia coli
-
-
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Substrate Product ID
ATP + UDP-N-acetylmuramoyl-L-Ala-D-Glu-L-Lys + D-Ala-D-Ala
-
986
Escherichia coli
ADP + phosphate + UDP-N-acetylmuramoyl-L-Ala-D-Glu-L-Lys-D-Ala-D-Ala
-
-
-
-
Subunits
Subunits
Commentary
Organism
?
x * 4792, nucleotide sequence
Escherichia coli
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ID
ATP + UDP-N-acetylmuramoyl-L-Ala-D-Glu-L-Lys + D-Ala-D-Ala
-
986
Escherichia coli
ADP + phosphate + UDP-N-acetylmuramoyl-L-Ala-D-Glu-L-Lys-D-Ala-D-Ala
-
-
-
-
Subunits (protein specific)
Subunits
Commentary
Organism
?
x * 4792, nucleotide sequence
Escherichia coli
Other publictions for EC 6.3.2.10
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Synonyms
Temperature Optimum [C]
Temperature Range [C]
Temperature Stability [C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [C] (protein specific)
Temperature Range [C] (protein specific)
Temperature Stability [C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
743956
An
Purification, crystallization ...
Acinetobacter baumannii, Acinetobacter baumannii AB307-0294
Acta Crystallogr. Sect. F
70
976-978
2014
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1
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1
1
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4
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1
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1
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2
1
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2
2
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744222
Cha
ATP-binding mode including a ...
Acinetobacter baumannii, Acinetobacter baumannii AB307-0294
Biochem. Biophys. Res. Commun.
450
1045-1050
2014
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1
1
1
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1
1
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3
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1
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6
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3
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1
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1
1
1
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1
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6
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1
1
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701735
Baum
MurF inhibitors with antibacte ...
Escherichia coli
Antimicrob. Agents Chemother.
53
3240-3247
2009
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1
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702541
Sova
Phosphorylated hydroxyethylami ...
Escherichia coli
Bioorg. Chem.
37
217-222
2009
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1
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1
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702636
Turk
Discovery of new inhibitors of ...
Escherichia coli
Bioorg. Med. Chem.
17
1884-1889
2009
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1
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681042
Khedkar
Design of inhibitors of the Mu ...
Streptococcus pneumoniae
J. Chem. Inf. Model.
47
1839-1846
2007
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31
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1
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1
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22
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22
31
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677589
Baum
Utility of muropeptide ligase ...
Escherichia coli
Antimicrob. Agents Chemother.
50
230-236
2006
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1
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3
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1
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1
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1
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3
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3
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679177
Stamper
Structure-based optimization o ...
Streptococcus pneumoniae
Chem. Biol. Drug Des.
67
58-65
2006
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1
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1
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6
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1
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1
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6
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1
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1
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6
6
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680459
Sobral
Role of murF in cell wall bios ...
Staphylococcus aureus
J. Bacteriol.
188
2543-2553
2006
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680941
Comess
An ultraefficient affinity-bas ...
Streptococcus pneumoniae
J. Biomol. Screen.
11
743-754
2006
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1
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4
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1
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4
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661790
Serina
Glycopeptide resistance determ ...
Actinoplanes teichomyceticus
FEMS Microbiol. Lett.
240
69-74
2004
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1
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5
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1
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651110
Dementin
Evidence of a functional requi ...
Escherichia coli
Eur. J. Biochem.
268
5800-5807
2001
6
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1
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1
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8
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1
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1
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1
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1
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17
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1
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6
1
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1
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1
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6
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1
1
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1
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8
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1
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1
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17
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1
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1
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1
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649111
Yan
Crystallization and preliminar ...
Escherichia coli, Escherichia coli K37
Acta Crystallogr. Sect. D
55
2033-2034
1999
-
1
1
1
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1
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2
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1
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4
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7
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649829
Eveland
Conditionally lethal Escherich ...
Escherichia coli
Biochemistry
36
6223-6229
1997
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1
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8
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3
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1
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1
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4
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4
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7
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1
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1
1
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8
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3
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4
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4
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986
Parquet
Nucleotide sequence of the mur ...
Escherichia coli
Nucleic Acids Res.
17
5379
1989
-
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1
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1
1
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1
1
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987
Walsh
Enzymes in the D-alanine branc ...
Escherichia coli
J. Biol. Chem.
264
2393-2396
1989
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2
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1
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984
Oppenheim
Formation of D-alanyl-D-alanin ...
Enterococcus faecalis, Staphylococcus aureus
FEBS Lett.
48
172-175
1974
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2
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2
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4
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985
Linnett
Cell wall polymers of Bacillus ...
Lysinibacillus sphaericus, Lysinibacillus sphaericus 9602
J. Bacteriol.
120
342-354
1974
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4
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