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Literature summary for 6.3.1.2 extracted from
- Expression level of glutamine synthetase is increased in hepatocellular carcinoma and liver tissue with cirrhosis and chronic hepatitis B (2011), Hepatol. Int., 5, 698-706.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | expression of glutathione synthetase is observed in 70% of hepatocellular carcinoma patients, 46.7% of chronic hepatitis B stage 4 patients and 38% of chronic hepatitis B stage 1-3 patients. There is significant difference between hepatocellular carcinoma samples and non-tumor tissues. Serum glutathione synthetase levels are increased in hepatocellular carcinoma and chronic hepatitis B stage 1-4 patients. There are significant differences among all samples, except chronic hepatitis B stage 1-3 versus chronic hepatitis B stage 4. Hepatocellular carcinoma, chronic hepatitis B stage 1-4 and AFP are significantly associated with serum glutathione synthetase levels. In hepatocellular carcinoma group, TNM and Child-Pugh are significantly associated with glutathione synthetase levels. Expression of glutathione synthetase is increased in hepatocellular carcinoma, liver cirrhosis, and chronic hepatitis B | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Homo sapiens | - |
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