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BRENDA support

Literature summary for 6.3.1.13 extracted from

  • Gutierrez-Lugo, M.T.; Bewley, C.A.
    Susceptibility and mode of binding of the Mycobacterium tuberculosis cysteinyl transferase mycothiol ligase to tRNA synthetase inhibitors (2011), Bioorg. Med. Chem. Lett., 21, 2480-2483.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
cysteinyl sulfamoyl adenosine selective, discrimination of aminoacyl-t-RNA synthetase inhibitors occurs at the amino acid moiety Mycobacterium tuberculosis
additional information not inhibitory: aminoacyl-t-RNA synthetase inhibitors ochratoxin A, borrelidin, cispentacin, mupirocin, seryl ulfamoyl adenosine, aspartyl ulfamoyl adenosine Mycobacterium tuberculosis

Organism

Organism UniProt Comment Textmining
Mycobacterium tuberculosis
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-
-

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.00005
-
pH not specified in the publication, temperature not specified in the publication Mycobacterium tuberculosis cysteinyl sulfamoyl adenosine