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Literature summary for 6.2.2.2 extracted from

  • Koehnke, J.; Bent, A.F.; Zollman, D.; Smith, K.; Houssen, W.E.; Zhu, X.; Mann, G.; Lebl, T.; Scharff, R.; Shirran, S.; Botting, C.H.; Jaspars, M.; Schwarz-Linek, U.; Naismith, J.H.
    The cyanobactin heterocyclase enzyme a processive adenylase that operates with a defined order of reaction (2013), Angew. Chem. Int. Ed. Engl., 52, 13991-13996.
    View publication on PubMed
Search for more literature for 6.2.2.2

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli uncultured Prochloron sp. 06037A

Crystallization (Commentary)

Crystallization (Comment) Organism
structure of TruD at 2.9 A resolution. TruD forms an extended, curved molecule that exists as a dimer uncultured Prochloron sp. 06037A

Organism

Organism UniProt Comment Textmining
uncultured Prochloron sp. 06037A B2KYG8
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-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + a [PatE2]-(L-amino acyl-L-cysteine) engineered PatE2 protein with single core peptide sequence ITACITFC uncultured Prochloron sp. 06037A AMP + diphosphate + a [PatE2]-(1S,4R)-2-(C-substituted-aminomethyl)-4-acyl-2-thiazoline
-
 ?
additional information TruD is an adenylase, not a kinase. TruD operates in strict order with the terminal cysteine in the core peptide reacting first, the next most C-terminal cysteine then reacts, and so on uncultured Prochloron sp. 06037A ?
-
 ?

Subunits

Subunits Comment Organism
dimer crystallization data uncultured Prochloron sp. 06037A

Synonyms

Synonyms Comment Organism
TruD
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 uncultured Prochloron sp. 06037A