Any feedback?
Literature summary for 6.2.1.76 extracted from
- A plant malonyl-CoA synthetase enhances lipid content and polyketide yield in yeast cells (2014), Appl. Microbiol. Biotechnol., 98, 5435-5447 .
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| overexpression in Saccharomyces cerevisiae | Arabidopsis thaliana |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + malonate + CoA | Arabidopsis thaliana | - |
AMP + diphosphate + malonyl-CoA | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Arabidopsis thaliana | Q8H151 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + malonate + CoA | - |
Arabidopsis thaliana | AMP + diphosphate + malonyl-CoA | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| AAE13 | - |
Arabidopsis thaliana |
| At3g16170 | - |
Arabidopsis thaliana |
| malonyl-CoA synthetase | - |
Arabidopsis thaliana |
General Information
| General Information | Comment | Organism |
|---|---|---|
| metabolism | overexpression of a malonyl-CoA synthetase leads to significant increase in both lipid and polyketide accumulation. AAE13 expression increases lipid accumulation. Overexpression of AAE13 leads to significant increases in resveratrol accumulation. Overexpression of AAE13 suppresses the TCA cycle in transgenic yeast | Arabidopsis thaliana |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2026.1 (March 2026)
Legal
Curated at
Member of
![DSMZ Digital Diversity]()
![Global Core Biodata Resource]()
![ELIXIR Core Data Resource]()
![German Network for Bioinformatics Infrastructure]()
