Literature summary for 6.2.1.7 extracted from

Kirkpatrick, R.B.; Robinson,S.F.; Killenberg, P.G.
Diurnal variation of rat liver enzymes catalyzing bile acid conjugation and sulfation (1980), Biochim. Biophys. Acta, 620, 627-630.

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + cholate + CoA	Rattus norvegicus	choloyl-CoA synthetase is probably the rate limiting enzyme in the two-enzyme sequence catalyzing conjugation of bile acids	AMP + diphosphate + choloyl-CoA	-	?

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
liver	a circadian rhythm is noted in the enzyme activity	Rattus norvegicus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + cholate + CoA	choloyl-CoA synthetase is probably the rate limiting enzyme in the two-enzyme sequence catalyzing conjugation of bile acids	Rattus norvegicus	AMP + diphosphate + choloyl-CoA	-	?

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Release 2023.1 (January 2023)