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Literature summary for 6.2.1.7 extracted from

  • Vessey, D.A.; Benfatto, A.M.; Zerweck, E.; Vestweber, C.
    Purification and characterization of the enzymes of bile acid conjugation from fish liver (1990), Comp. Biochem. Physiol. B, 95, 647-652.
    View publication on PubMed

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.04
-
lithocholate
-
Ophiodon elongatus
0.05
-
cholate
-
Ophiodon elongatus
0.053
-
deoxycholate
-
Ophiodon elongatus
0.08
-
chenodeoxycholate
-
Ophiodon elongatus

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
Sebastes miniatus
-
-
microsome
-
Sebastes pinniger
-
-
microsome
-
Ophiodon elongatus
-
-

Organism

Organism UniProt Comment Textmining
Ophiodon elongatus
-
-
-
Sebastes miniatus
-
-
-
Sebastes pinniger
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Ophiodon elongatus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Sebastes miniatus
-
liver
-
Sebastes pinniger
-
liver
-
Ophiodon elongatus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.0015
-
-
Ophiodon elongatus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + chenodeoxycholate + CoA
-
Ophiodon elongatus AMP + diphosphate + chenodeoxycholoyl-CoA
-
?
ATP + cholate + CoA
-
Sebastes miniatus AMP + diphosphate + choloyl-CoA
-
?
ATP + cholate + CoA
-
Sebastes pinniger AMP + diphosphate + choloyl-CoA
-
?
ATP + cholate + CoA
-
Ophiodon elongatus AMP + diphosphate + choloyl-CoA
-
?
ATP + deoxycholate + CoA
-
Ophiodon elongatus AMP + diphosphate + deoxycholoyl-CoA
-
?
ATP + lithocholate + CoA
-
Ophiodon elongatus AMP + diphosphate + lithocholoyl-CoA
-
?

Subunits

Subunits Comment Organism
? 3 bands detected after SDS-PAGE, MW 40000, MW 50000 and MW 60000 Ophiodon elongatus