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Literature summary for 6.2.1.59 extracted from

  • Hernandez Pando, R.; Shin, S.J.; Clark, S.; Casonato, S.; Zambrano, M.B.; Kim, H.; Boldrin, F.; Mata Espinoza, D.; Provvedi, R.; Arbues, A.; Marquina Castillo, B.; Cioetto Mazzabo, L.; Barrios Payan, J.; Martin, C.; Cho, S.N.; Williams, A.; Manganelli, R.
    Construction and characterization of the double unmarked Mycobacterium tuberculosis mutant sigE/fadD26 as a vaccine candidate (2019), Infect. Immun., 88, e00496 .
    View publication on PubMedView publication on EuropePMC
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Application

Application Comment Organism
medicine a SigE/FadD26 double mutant is more attenuated and more efficacious than wild-type strain BCG BCG in a mouse model of infection, and equivalent to BCG in a Guinea pig model of infection Mycobacterium tuberculosis variant bovis

Organism

Organism UniProt Comment Textmining
Mycobacterium tuberculosis variant bovis A0A0H3M8A6
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