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Literature summary for 6.2.1.55 extracted from

  • Chavarria, N.E.; Hwang, S.; Cao, S.; Fu, X.; Holman, M.; Elbanna, D.; Rodriguez, S.; Arrington, D.; Englert, M.; Uthandi, S.; Söll, D.; Maupin-Furlow, J.A.
    Archaeal Tuc1/Ncs6 homolog required for wobble uridine tRNA thiolation is associated with ubiquitin-proteasome, translation, and RNA processing system homologs (2014), PLoS One, 9, e99104.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 6.2.1.55

Organism

Organism UniProt Comment Textmining
Haloferax volcanii D4GSF3
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Haloferax volcanii DSM 3757 D4GSF3
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + [SAMP2]-Gly-Gly + [NcsA protein]-L-lysine NcsA is an archaeal homolog of the cytoplasmic tRNA 2-thiolation protein 1 (Tuc1/Ncs6). NcsA is essential for growth at high temperature and required for formation of thiolated tRNALys UUU. NcsA is modified at Lys204 by isopeptide linkage to polymeric chains of the ubiquitin-fold protein SAMP2 Haloferax volcanii AMP + diphosphate + N6-[[SAMP2]-Gly-Gly]-[[NcsA protein]-L-lysine]
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ATP + [SAMP2]-Gly-Gly + [NcsA protein]-L-lysine NcsA is an archaeal homolog of the cytoplasmic tRNA 2-thiolation protein 1 (Tuc1/Ncs6). NcsA is essential for growth at high temperature and required for formation of thiolated tRNALys UUU. NcsA is modified at Lys204 by isopeptide linkage to polymeric chains of the ubiquitin-fold protein SAMP2 Haloferax volcanii DSM 3757 AMP + diphosphate + N6-[[SAMP2]-Gly-Gly]-[[NcsA protein]-L-lysine]
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Synonyms

Synonyms Comment Organism
HVO_0558 locus name Haloferax volcanii
UbaA ubiquitin-activating E1 enzyme homolog of archaea Haloferax volcanii