Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Mycobacterium tuberculosis |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-hydroxybenzoyl-adenylate + holo-[4-hydroxyphenylalkanoate synthase] | Mycobacterium tuberculosis | - |
AMP + 4-hydroxybenzoyl-[4-hydroxyphenylalkanoate synthase] | - |
? | |
4-hydroxybenzoyl-adenylate + holo-[4-hydroxyphenylalkanoate synthase] | Mycobacterium tuberculosis H37Rv | - |
AMP + 4-hydroxybenzoyl-[4-hydroxyphenylalkanoate synthase] | - |
? | |
ATP + 4-hydroxybenzoate | Mycobacterium tuberculosis | - |
4-hydroxybenzoyl-adenylate + diphosphate | - |
? | |
ATP + 4-hydroxybenzoate | Mycobacterium tuberculosis H37Rv | - |
4-hydroxybenzoyl-adenylate + diphosphate | - |
? | |
ATP + 4-hydroxybenzoate + holo-[4-hydroxyphenylalkanoate synthase] | Mycobacterium tuberculosis | - |
AMP + diphosphate + 4-hydroxybenzoyl-[4-hydroxyphenylalkanoate synthase] | - |
? | |
ATP + 4-hydroxybenzoate + holo-[4-hydroxyphenylalkanoate synthase] | Mycobacterium tuberculosis H37Rv | - |
AMP + diphosphate + 4-hydroxybenzoyl-[4-hydroxyphenylalkanoate synthase] | - |
? | |
additional information | Mycobacterium tuberculosis | FadD22 displays a 4-hydroxybenzoyl-AMP ligase activity. No substrate: laurate | ? | - |
? | |
additional information | Mycobacterium tuberculosis H37Rv | FadD22 displays a 4-hydroxybenzoyl-AMP ligase activity. No substrate: laurate | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mycobacterium tuberculosis | P9WQ61 | - |
- |
Mycobacterium tuberculosis H37Rv | P9WQ61 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-hydroxybenzoyl-adenylate + holo-[4-hydroxyphenylalkanoate synthase] | - |
Mycobacterium tuberculosis | AMP + 4-hydroxybenzoyl-[4-hydroxyphenylalkanoate synthase] | - |
? | |
4-hydroxybenzoyl-adenylate + holo-[4-hydroxyphenylalkanoate synthase] | - |
Mycobacterium tuberculosis H37Rv | AMP + 4-hydroxybenzoyl-[4-hydroxyphenylalkanoate synthase] | - |
? | |
ATP + 4-hydroxybenzoate | - |
Mycobacterium tuberculosis | 4-hydroxybenzoyl-adenylate + diphosphate | - |
? | |
ATP + 4-hydroxybenzoate | - |
Mycobacterium tuberculosis H37Rv | 4-hydroxybenzoyl-adenylate + diphosphate | - |
? | |
ATP + 4-hydroxybenzoate + holo-[4-hydroxyphenylalkanoate synthase] | - |
Mycobacterium tuberculosis | AMP + diphosphate + 4-hydroxybenzoyl-[4-hydroxyphenylalkanoate synthase] | - |
? | |
ATP + 4-hydroxybenzoate + holo-[4-hydroxyphenylalkanoate synthase] | - |
Mycobacterium tuberculosis H37Rv | AMP + diphosphate + 4-hydroxybenzoyl-[4-hydroxyphenylalkanoate synthase] | - |
? | |
additional information | FadD22 displays a 4-hydroxybenzoyl-AMP ligase activity. No substrate: laurate | Mycobacterium tuberculosis | ? | - |
? | |
additional information | FadD22 displays a 4-hydroxybenzoyl-AMP ligase activity. No substrate: laurate | Mycobacterium tuberculosis H37Rv | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
fadD22 | - |
Mycobacterium tuberculosis |
p-hydroxybenzoic acid-AMP ligase | - |
Mycobacterium tuberculosis |
General Information | Comment | Organism |
---|---|---|
physiological function | disruption of FadD22 abolishes the production of its species-specific phenolic glycolipid | Mycobacterium tuberculosis |