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Literature summary for 6.2.1.5 extracted from
- Drosophila ortholog of succinyl-CoA synthetase {beta} subunit: a novel modulator of Drosophila KCNQ channels (2008), J. Neurophysiol., 99, 2736-2740.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| gene CG11963, expression as GST-tagged enzyme in Escherichia coli strain BL21(DE3), interaction analysis of Myc-tagged CG11963 and FLAG-tagged dKCNQ using the yeast two-hybrid system | Drosophila melanogaster |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | - |
Drosophila melanogaster |  |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + acetate + CoA | Drosophila melanogaster | - |
ADP + phosphate + acetyl-CoA | - |
? | |
| additional information | Drosophila melanogaster | a Drosophila orthologue of succinyl-CoA synthetase beta-subunit is a modulator of Drosophila KCNQ channels responsible for slowly activating potassium currents in heart, brain, and other tissues, direct interaction with the intracellular C-terminal tail KCNQ channel, overview | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Drosophila melanogaster | - |
gene CG11963 | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + acetate + CoA | - |
Drosophila melanogaster | ADP + phosphate + acetyl-CoA | - |
? | |
| additional information | a Drosophila orthologue of succinyl-CoA synthetase beta-subunit is a modulator of Drosophila KCNQ channels responsible for slowly activating potassium currents in heart, brain, and other tissues, direct interaction with the intracellular C-terminal tail KCNQ channel, overview | Drosophila melanogaster | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| CG11963 | - |
Drosophila melanogaster |
| Succinyl-CoA synthetase | - |
Drosophila melanogaster |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| ATP | - |
Drosophila melanogaster | |
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Release 2023.1 (January 2023)
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