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Literature summary for 6.2.1.45 extracted from
- Designed semisynthetic protein inhibitors of Ub/Ubl E1 activating enzymes (2010), J. Am. Chem. Soc., 17, 1748-1749.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 5'-[[(L-cysteinylglycylglycyl)sulfamoyl]amino]-5'-deoxyadenosine | inhibits Uba1-S-Ub thioester formation in a dose-dependent manner. The inhibitor is highly selective for its cognate E1 enzyme and does not inhibit the corresponding non-cognate E1s | Schizosaccharomyces pombe |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Schizosaccharomyces pombe | - |
- |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Ub E1 activating enzyme | - |
Schizosaccharomyces pombe |
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Release 2023.1 (January 2023)
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