Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Rattus norvegicus | 5739 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
GDP + phosphate + succinyl-CoA | Rattus norvegicus | GTP generated by the activation of succinyl-CoA synthetase could promote key functional roles in the mitochondrial metabolism leading to insulin secretion | GTP + succinate + CoA | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
phosphoprotein | the alpha-subunit of succinyl-CoA synthetase undergoes autophosphorylation at a histidine residue. Coprovision of exogenous succinate and CoA results in pronounced dephosphorylation of the phosphorylated alpha-subunit of succinyl-CoA synthetase | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HIT-T15 cell | two distinct ATP-specific and GTP-specific succinyl-CoA synthetases | Rattus norvegicus | - |
INS-1 cell | two distinct ATP-specific and GTP-specific succinyl-CoA synthetases | Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
GDP + phosphate + succinyl-CoA | GTP generated by the activation of succinyl-CoA synthetase could promote key functional roles in the mitochondrial metabolism leading to insulin secretion | Rattus norvegicus | GTP + succinate + CoA | - |
? | |
GTP + succinate + CoA | - |
Rattus norvegicus | GDP + phosphate + succinyl-CoA | - |
? |