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Literature summary for 6.2.1.3 extracted from

  • Vanden Heuvel, J.P.; Kuslikis, B.I.; Shrago, E.; Peterson, R.E.
    Inhibition of long-chain acyl-CoA synthetase by the peroxisome proliferator perfluorodecanoic acid in rat hepatocytes (1991), Biochem. Pharmacol., 42, 295-302.
    View publication on PubMed
Search for more literature for 6.2.1.3

Inhibitors

Inhibitors Comment Organism Structure
Perfluorodecanoic acid no inhibition by short-chain perfluorinated fatty acids Rattus norvegicus
Perfluorononanoic acid no inhibition by short-chain perfluorinated fatty acids Rattus norvegicus
Perfluorooctanoic acid no inhibition by short-chain perfluorinated fatty acids Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + long-chain carboxylic acid + CoA Rattus norvegicus enzyme is essential for both oxidation and esterification of fatty acids ?
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
hepatocyte
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + long-chain carboxylic acid + CoA enzyme is essential for both oxidation and esterification of fatty acids Rattus norvegicus ?
-
 ?
ATP + palmitate + CoA
-
 Rattus norvegicus AMP + diphosphate + palmitoyl-CoA
-
 ?