Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Triacsin A | isolated from the culture filtrate of Streptomyces sp. SK-1894, the anti-atherosclerotic agent acts as selective enzyme inhibitor, it inhibits the synthesis of cholesteryl ester and triacylglycerol in peritoneal macrophages | Mus musculus | |
Triacsin C | isolated from the culture filtrate of Streptomyces sp. SK-1894, the anti-atherosclerotic agent acts as selective enzyme inhibitor, it inhibits the synthesis of cholesteryl ester and triacylglycerol in peritoneal macrophages | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
macrophage | peritoneal | Mus musculus | - |
Synonyms | Comment | Organism |
---|---|---|
ACS | - |
Mus musculus |
Acyl-CoA synthetase | - |
Mus musculus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0001 | - |
inhibition of triacylglycerol synthesis | Mus musculus | Triacsin C | |
0.00016 | - |
inhibition of triacylglycerol synthesis | Mus musculus | Triacsin A | |
0.00018 | - |
inhibition of cholesteryl ester synthesis | Mus musculus | Triacsin A | |
0.00019 | - |
inhibition of cholesteryl ester synthesis | Mus musculus | Triacsin C |