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Literature summary for 6.2.1.3 extracted from
- The role of long-chain fatty-acid-CoA ligase 3 in vitamin D3 and androgen control of prostate cancer LNCaP cell growth (2004), Biochem. Biophys. Res. Commun., 319, 358-368.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Homo sapiens | the regulation of the FACL3/ACS3 expression by vitamin D3 is mediated by both androgen and androgen receptor, and suggests that increased FACL3/ACS3 expression by vitamin D3 is one of the components associated with antiproliferative effect of 1alpha,25(OH)2D3 in androgen receptor-positive prostate cancer LNCaP cells | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| LNCaP cell | FACL3/ACS3 is the dominant isoform of FACL/ACS expressed in LNCaP cells | Homo sapiens | - |
| prostate cancer cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | the regulation of the FACL3/ACS3 expression by vitamin D3 is mediated by both androgen and androgen receptor, and suggests that increased FACL3/ACS3 expression by vitamin D3 is one of the components associated with antiproliferative effect of 1alpha,25(OH)2D3 in androgen receptor-positive prostate cancer LNCaP cells | Homo sapiens | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| FACL3/ACS3 | - |
Homo sapiens |
| long-chain fatty-acid-CoA ligase 3 | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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