Cloned (Comment) | Organism |
---|---|
gene prpE, functional expression in Sorangium cellulosum So ce90 leading to a significant increase in the resolution of epothilones B/A, with an epothilone B to A ratio of 127 to 1, which is 100times higher than that of the wild-type cells | Ralstonia solanacearum |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | - |
Ralstonia solanacearum |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + propanoate + CoA | Ralstonia solanacearum | propionyl-CoA is a potent precursor of epothilone B, a potential anti-cancer agent | AMP + diphosphate + propanoyl-CoA | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Ralstonia solanacearum | - |
gene prpE | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + propanoate + CoA | - |
Ralstonia solanacearum | AMP + diphosphate + propanoyl-CoA | - |
? | |
ATP + propanoate + CoA | propionyl-CoA is a potent precursor of epothilone B, a potential anti-cancer agent | Ralstonia solanacearum | AMP + diphosphate + propanoyl-CoA | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Propionyl-CoA synthetase | - |
Ralstonia solanacearum |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Ralstonia solanacearum |