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Literature summary for 6.2.1.12 extracted from
- Properties of hydroxycinnamate:CoA ligase from stems of Salix babylonica cultured in vitro (1984), Phytochemistry, 23, 1557-1559.
No PubMed abstract available
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 4-coumarate | inhibition above 0.6 mM | Salix babylonica |  |
| caffeate | inhibition above 0.2 mM | Salix babylonica | |
| ferulate | inhibition above 0.4 mM | Salix babylonica | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.0047 | - |
ferulate | - |
Salix babylonica | |
| 0.031 | - |
4-coumarate | - |
Salix babylonica | |
| 0.032 | - |
4-coumarate | ATP | Salix babylonica | |
| 0.046 | - |
ferulate | - |
Salix babylonica | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | required | Salix babylonica | |
| Mg2+ | optimal concentration 10 mM | Salix babylonica | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 57000 | - |
gel filtration | Salix babylonica |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + 4-coumarate + CoA | Salix babylonica | physiological role in lignin biosynthesis | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Salix babylonica | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Salix babylonica |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| stem | - |
Salix babylonica | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + 4-coumarate + CoA | - |
Salix babylonica | AMP + diphosphate + 4-coumaroyl-CoA | - |
? | |
| ATP + 4-coumarate + CoA | physiological role in lignin biosynthesis | Salix babylonica | ? | - |
? | |
| ATP + caffeate + CoA | - |
Salix babylonica | AMP + diphosphate + caffeoyl-CoA | - |
? | |
| ATP + ferulate + CoA | - |
Salix babylonica | AMP + diphosphate + feruloyl-CoA | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7 | - |
- |
Salix babylonica |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 6.2 | 8 | half-maximum activity at pH 6.2 and 8 | Salix babylonica |
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