BRENDA - Enzyme Database
show all sequences of 6.1.3.1

beta-Lactone synthetase found in the olefin biosynthesis pathway

Christenson, J.K.; Richman, J.E.; Jensen, M.R.; Neufeld, J.Y.; Wilmot, C.M.; Wackett, L.P.; Biochemistry 56, 348-351 (2017)

Data extracted from this reference:

Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ATP + (2R)-2-[(1R)-1-hydroxydecyl]decanoic acid
Stenotrophomonas maltophilia
-
AMP + diphosphate + trans-3-octyl-4-nonyloxetan-2-one
-
-
?
ATP + (2R)-2-[(1R)-1-hydroxydecyl]decanoic acid
Xanthomonas campestris
-
AMP + diphosphate + trans-3-octyl-4-nonyloxetan-2-one
-
-
?
ATP + (2R)-2-[(1R)-1-hydroxydecyl]decanoic acid
Arenimonas malthae
-
AMP + diphosphate + trans-3-octyl-4-nonyloxetan-2-one
-
-
?
ATP + (2R)-2-[(1R)-1-hydroxydecyl]decanoic acid
Lysobacter dokdonensis
-
AMP + diphosphate + trans-3-octyl-4-nonyloxetan-2-one
-
-
?
ATP + (2R)-2-[(1R)-1-hydroxydecyl]decanoic acid
Micrococcus luteus
-
AMP + diphosphate + trans-3-octyl-4-nonyloxetan-2-one
-
-
?
ATP + (2R)-2-[(1R)-1-hydroxydecyl]decanoic acid
Micrococcus luteus ATCC4698
-
AMP + diphosphate + trans-3-octyl-4-nonyloxetan-2-one
-
-
?
ATP + (2S)-2-[(1R)-1-hydroxydecyl]decanoic acid
Stenotrophomonas maltophilia
-
AMP + diphosphate + cis-3-octyl-4-nonyloxetan-2-one
-
-
?
ATP + (2S)-2-[(1R)-1-hydroxydecyl]decanoic acid
Xanthomonas campestris
-
AMP + diphosphate + cis-3-octyl-4-nonyloxetan-2-one
-
-
?
ATP + (2S)-2-[(1R)-1-hydroxydecyl]decanoic acid
Arenimonas malthae
-
AMP + diphosphate + cis-3-octyl-4-nonyloxetan-2-one
-
-
?
ATP + (2S)-2-[(1R)-1-hydroxydecyl]decanoic acid
Lysobacter dokdonensis
-
AMP + diphosphate + cis-3-octyl-4-nonyloxetan-2-one
-
-
?
ATP + (2S)-2-[(1R)-1-hydroxydecyl]decanoic acid
Micrococcus luteus
-
AMP + diphosphate + cis-3-octyl-4-nonyloxetan-2-one
-
-
?
ATP + (2S)-2-[(1R)-1-hydroxydecyl]decanoic acid
Micrococcus luteus ATCC4698
-
AMP + diphosphate + cis-3-octyl-4-nonyloxetan-2-one
-
-
?
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Arenimonas malthae
A0A091B3V8
-
-
Lysobacter dokdonensis
A0A0A2WK72
-
-
Micrococcus luteus
C5CCL7
-
-
Micrococcus luteus ATCC4698
C5CCL7
-
-
Stenotrophomonas maltophilia
-
-
-
Xanthomonas campestris
WP_011035474
-
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ATP + (2R)-2-[(1R)-1-hydroxydecyl]decanoic acid
-
741939
Stenotrophomonas maltophilia
AMP + diphosphate + trans-3-octyl-4-nonyloxetan-2-one
-
-
-
?
ATP + (2R)-2-[(1R)-1-hydroxydecyl]decanoic acid
-
741939
Xanthomonas campestris
AMP + diphosphate + trans-3-octyl-4-nonyloxetan-2-one
-
-
-
?
ATP + (2R)-2-[(1R)-1-hydroxydecyl]decanoic acid
-
741939
Arenimonas malthae
AMP + diphosphate + trans-3-octyl-4-nonyloxetan-2-one
-
-
-
?
ATP + (2R)-2-[(1R)-1-hydroxydecyl]decanoic acid
-
741939
Lysobacter dokdonensis
AMP + diphosphate + trans-3-octyl-4-nonyloxetan-2-one
-
-
-
?
ATP + (2R)-2-[(1R)-1-hydroxydecyl]decanoic acid
-
741939
Micrococcus luteus
AMP + diphosphate + trans-3-octyl-4-nonyloxetan-2-one
-
-
-
?
ATP + (2R)-2-[(1R)-1-hydroxydecyl]decanoic acid
-
741939
Micrococcus luteus ATCC4698
AMP + diphosphate + trans-3-octyl-4-nonyloxetan-2-one
-
-
-
?
ATP + (2S)-2-[(1R)-1-hydroxydecyl]decanoic acid
-
741939
Stenotrophomonas maltophilia
AMP + diphosphate + cis-3-octyl-4-nonyloxetan-2-one
-
-
-
?
ATP + (2S)-2-[(1R)-1-hydroxydecyl]decanoic acid
-
741939
Xanthomonas campestris
AMP + diphosphate + cis-3-octyl-4-nonyloxetan-2-one
-
-
-
?
ATP + (2S)-2-[(1R)-1-hydroxydecyl]decanoic acid
-
741939
Arenimonas malthae
AMP + diphosphate + cis-3-octyl-4-nonyloxetan-2-one
-
-
-
?
ATP + (2S)-2-[(1R)-1-hydroxydecyl]decanoic acid
-
741939
Lysobacter dokdonensis
AMP + diphosphate + cis-3-octyl-4-nonyloxetan-2-one
-
-
-
?
ATP + (2S)-2-[(1R)-1-hydroxydecyl]decanoic acid
-
741939
Micrococcus luteus
AMP + diphosphate + cis-3-octyl-4-nonyloxetan-2-one
-
-
-
?
ATP + (2S)-2-[(1R)-1-hydroxydecyl]decanoic acid
-
741939
Micrococcus luteus ATCC4698
AMP + diphosphate + cis-3-octyl-4-nonyloxetan-2-one
-
-
-
?
additional information
OleC proteins produce thermally labile beta-lactones from beta-hydroxy acids in an ATP-dependent reaction. MgATP is likely required to activate the hydroxyl or carboxyl group and promote beta-lactone ring formation. All four beta-hydroxy acid isomers are utilized by OleC
741939
Stenotrophomonas maltophilia
?
-
-
-
-
additional information
OleC proteins produce thermally labile beta-lactones from beta-hydroxy acids in an ATP-dependent reaction. MgATP is likely required to activate the hydroxyl or carboxyl group and promote beta-lactone ring formation. All four beta-hydroxy acid isomers are utilized by OleC
741939
Xanthomonas campestris
?
-
-
-
-
additional information
OleC proteins produce thermally labile beta-lactones from beta-hydroxy acids in an ATP-dependent reaction. MgATP is likely required to activate the hydroxyl or carboxyl group and promote beta-lactone ring formation. All four beta-hydroxy acid isomers are utilized by OleC
741939
Arenimonas malthae
?
-
-
-
-
additional information
OleC proteins produce thermally labile beta-lactones from beta-hydroxy acids in an ATP-dependent reaction. MgATP is likely required to activate the hydroxyl or carboxyl group and promote beta-lactone ring formation. All four beta-hydroxy acid isomers are utilized by OleC
741939
Lysobacter dokdonensis
?
-
-
-
-
additional information
OleC proteins produce thermally labile beta-lactones from beta-hydroxy acids in an ATP-dependent reaction. MgATP is likely required to activate the hydroxyl or carboxyl group and promote beta-lactone ring formation. All four beta-hydroxy acid isomers are utilized by OleC
741939
Micrococcus luteus
?
-
-
-
-
additional information
OleC proteins produce thermally labile beta-lactones from beta-hydroxy acids in an ATP-dependent reaction. MgATP is likely required to activate the hydroxyl or carboxyl group and promote beta-lactone ring formation. All four beta-hydroxy acid isomers are utilized by OleC
741939
Micrococcus luteus ATCC4698
?
-
-
-
-
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ATP + (2R)-2-[(1R)-1-hydroxydecyl]decanoic acid
Stenotrophomonas maltophilia
-
AMP + diphosphate + trans-3-octyl-4-nonyloxetan-2-one
-
-
?
ATP + (2R)-2-[(1R)-1-hydroxydecyl]decanoic acid
Xanthomonas campestris
-
AMP + diphosphate + trans-3-octyl-4-nonyloxetan-2-one
-
-
?
ATP + (2R)-2-[(1R)-1-hydroxydecyl]decanoic acid
Arenimonas malthae
-
AMP + diphosphate + trans-3-octyl-4-nonyloxetan-2-one
-
-
?
ATP + (2R)-2-[(1R)-1-hydroxydecyl]decanoic acid
Lysobacter dokdonensis
-
AMP + diphosphate + trans-3-octyl-4-nonyloxetan-2-one
-
-
?
ATP + (2R)-2-[(1R)-1-hydroxydecyl]decanoic acid
Micrococcus luteus
-
AMP + diphosphate + trans-3-octyl-4-nonyloxetan-2-one
-
-
?
ATP + (2R)-2-[(1R)-1-hydroxydecyl]decanoic acid
Micrococcus luteus ATCC4698
-
AMP + diphosphate + trans-3-octyl-4-nonyloxetan-2-one
-
-
?
ATP + (2S)-2-[(1R)-1-hydroxydecyl]decanoic acid
Stenotrophomonas maltophilia
-
AMP + diphosphate + cis-3-octyl-4-nonyloxetan-2-one
-
-
?
ATP + (2S)-2-[(1R)-1-hydroxydecyl]decanoic acid
Xanthomonas campestris
-
AMP + diphosphate + cis-3-octyl-4-nonyloxetan-2-one
-
-
?
ATP + (2S)-2-[(1R)-1-hydroxydecyl]decanoic acid
Arenimonas malthae
-
AMP + diphosphate + cis-3-octyl-4-nonyloxetan-2-one
-
-
?
ATP + (2S)-2-[(1R)-1-hydroxydecyl]decanoic acid
Lysobacter dokdonensis
-
AMP + diphosphate + cis-3-octyl-4-nonyloxetan-2-one
-
-
?
ATP + (2S)-2-[(1R)-1-hydroxydecyl]decanoic acid
Micrococcus luteus
-
AMP + diphosphate + cis-3-octyl-4-nonyloxetan-2-one
-
-
?
ATP + (2S)-2-[(1R)-1-hydroxydecyl]decanoic acid
Micrococcus luteus ATCC4698
-
AMP + diphosphate + cis-3-octyl-4-nonyloxetan-2-one
-
-
?
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ATP + (2R)-2-[(1R)-1-hydroxydecyl]decanoic acid
-
741939
Stenotrophomonas maltophilia
AMP + diphosphate + trans-3-octyl-4-nonyloxetan-2-one
-
-
-
?
ATP + (2R)-2-[(1R)-1-hydroxydecyl]decanoic acid
-
741939
Xanthomonas campestris
AMP + diphosphate + trans-3-octyl-4-nonyloxetan-2-one
-
-
-
?
ATP + (2R)-2-[(1R)-1-hydroxydecyl]decanoic acid
-
741939
Arenimonas malthae
AMP + diphosphate + trans-3-octyl-4-nonyloxetan-2-one
-
-
-
?
ATP + (2R)-2-[(1R)-1-hydroxydecyl]decanoic acid
-
741939
Lysobacter dokdonensis
AMP + diphosphate + trans-3-octyl-4-nonyloxetan-2-one
-
-
-
?
ATP + (2R)-2-[(1R)-1-hydroxydecyl]decanoic acid
-
741939
Micrococcus luteus
AMP + diphosphate + trans-3-octyl-4-nonyloxetan-2-one
-
-
-
?
ATP + (2R)-2-[(1R)-1-hydroxydecyl]decanoic acid
-
741939
Micrococcus luteus ATCC4698
AMP + diphosphate + trans-3-octyl-4-nonyloxetan-2-one
-
-
-
?
ATP + (2S)-2-[(1R)-1-hydroxydecyl]decanoic acid
-
741939
Stenotrophomonas maltophilia
AMP + diphosphate + cis-3-octyl-4-nonyloxetan-2-one
-
-
-
?
ATP + (2S)-2-[(1R)-1-hydroxydecyl]decanoic acid
-
741939
Xanthomonas campestris
AMP + diphosphate + cis-3-octyl-4-nonyloxetan-2-one
-
-
-
?
ATP + (2S)-2-[(1R)-1-hydroxydecyl]decanoic acid
-
741939
Arenimonas malthae
AMP + diphosphate + cis-3-octyl-4-nonyloxetan-2-one
-
-
-
?
ATP + (2S)-2-[(1R)-1-hydroxydecyl]decanoic acid
-
741939
Lysobacter dokdonensis
AMP + diphosphate + cis-3-octyl-4-nonyloxetan-2-one
-
-
-
?
ATP + (2S)-2-[(1R)-1-hydroxydecyl]decanoic acid
-
741939
Micrococcus luteus
AMP + diphosphate + cis-3-octyl-4-nonyloxetan-2-one
-
-
-
?
ATP + (2S)-2-[(1R)-1-hydroxydecyl]decanoic acid
-
741939
Micrococcus luteus ATCC4698
AMP + diphosphate + cis-3-octyl-4-nonyloxetan-2-one
-
-
-
?
additional information
OleC proteins produce thermally labile beta-lactones from beta-hydroxy acids in an ATP-dependent reaction. MgATP is likely required to activate the hydroxyl or carboxyl group and promote beta-lactone ring formation. All four beta-hydroxy acid isomers are utilized by OleC
741939
Stenotrophomonas maltophilia
?
-
-
-
-
additional information
OleC proteins produce thermally labile beta-lactones from beta-hydroxy acids in an ATP-dependent reaction. MgATP is likely required to activate the hydroxyl or carboxyl group and promote beta-lactone ring formation. All four beta-hydroxy acid isomers are utilized by OleC
741939
Xanthomonas campestris
?
-
-
-
-
additional information
OleC proteins produce thermally labile beta-lactones from beta-hydroxy acids in an ATP-dependent reaction. MgATP is likely required to activate the hydroxyl or carboxyl group and promote beta-lactone ring formation. All four beta-hydroxy acid isomers are utilized by OleC
741939
Arenimonas malthae
?
-
-
-
-
additional information
OleC proteins produce thermally labile beta-lactones from beta-hydroxy acids in an ATP-dependent reaction. MgATP is likely required to activate the hydroxyl or carboxyl group and promote beta-lactone ring formation. All four beta-hydroxy acid isomers are utilized by OleC
741939
Lysobacter dokdonensis
?
-
-
-
-
additional information
OleC proteins produce thermally labile beta-lactones from beta-hydroxy acids in an ATP-dependent reaction. MgATP is likely required to activate the hydroxyl or carboxyl group and promote beta-lactone ring formation. All four beta-hydroxy acid isomers are utilized by OleC
741939
Micrococcus luteus
?
-
-
-
-
additional information
OleC proteins produce thermally labile beta-lactones from beta-hydroxy acids in an ATP-dependent reaction. MgATP is likely required to activate the hydroxyl or carboxyl group and promote beta-lactone ring formation. All four beta-hydroxy acid isomers are utilized by OleC
741939
Micrococcus luteus ATCC4698
?
-
-
-
-
General Information
General Information
Commentary
Organism
physiological function
enzyme reacts with syn- and anti-beta-hydroxy acid substrates to yield cis- and trans-beta-lactones, respectively
Arenimonas malthae
physiological function
enzyme reacts with syn- and anti-beta-hydroxy acid substrates to yield cis- and trans-beta-lactones, respectively
Lysobacter dokdonensis
physiological function
enzyme reacts with syn- and anti-beta-hydroxy acid substrates to yield cis- and trans-beta-lactones, respectively
Micrococcus luteus
physiological function
enzyme reacts with syn- and anti-beta-hydroxy acid substrates to yield cis- and trans-beta-lactones, respectively
Stenotrophomonas maltophilia
physiological function
enzyme reacts with syn- and anti-beta-hydroxy acid substrates to yield cis- and trans-beta-lactones, respectively
Xanthomonas campestris
General Information (protein specific)
General Information
Commentary
Organism
physiological function
enzyme reacts with syn- and anti-beta-hydroxy acid substrates to yield cis- and trans-beta-lactones, respectively
Arenimonas malthae
physiological function
enzyme reacts with syn- and anti-beta-hydroxy acid substrates to yield cis- and trans-beta-lactones, respectively
Lysobacter dokdonensis
physiological function
enzyme reacts with syn- and anti-beta-hydroxy acid substrates to yield cis- and trans-beta-lactones, respectively
Micrococcus luteus
physiological function
enzyme reacts with syn- and anti-beta-hydroxy acid substrates to yield cis- and trans-beta-lactones, respectively
Stenotrophomonas maltophilia
physiological function
enzyme reacts with syn- and anti-beta-hydroxy acid substrates to yield cis- and trans-beta-lactones, respectively
Xanthomonas campestris
Other publictions for EC 6.1.3.1
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
741939
Christenson
beta-Lactone synthetase found ...
Arenimonas malthae, Lysobacter dokdonensis, Micrococcus luteus, Micrococcus luteus ATCC4698, Stenotrophomonas maltophilia, Xanthomonas campestris
Biochemistry
56
348-351
2017
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18
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12
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18
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5
5
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742797
Christenson
Active multienzyme assemblies ...
Xanthomonas campestris
J. Bacteriol.
199
e00890
2017
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1
-
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-
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1
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1
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1
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1
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1
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1
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1
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1
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742283
Kancharla
Stenotrophomonas maltophilia ...
Stenotrophomonas maltophilia
ChemBioChem
17
1426-1429
2016
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1
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4
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1
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4
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4
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1
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4
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4
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4
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1
1
-
4
4
741673
Sukovich
Structure, function, and insi ...
Shewanella oneidensis, Shewanella oneidensis MR-1 / ATCC 700550
Appl. Environ. Microbiol.
76
3842-3849
2010
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2
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1
1
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