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Literature summary for 6.1.2.1 extracted from

  • Kruse, T.; Levisson, M.; de Vos, W.M.; Smidt, H.
    vanI a novel D-Ala-D-Lac vancomycin resistance gene cluster found in Desulfitobacterium hafniense (2014), Microb. Biotechnol., 7, 456-466 .
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
D-alanine + (R)-lactate + ATP Desulfitobacterium hafniense
-
D-alanyl-(R)-lactate + ADP + phosphate
-
?
D-alanine + (R)-lactate + ATP Desulfitobacterium hafniense Y51
-
D-alanyl-(R)-lactate + ADP + phosphate
-
?

Organism

Organism UniProt Comment Textmining
Desulfitobacterium hafniense
-
-
-
Desulfitobacterium hafniense Y51
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
D-alanine + (R)-lactate + ATP
-
Desulfitobacterium hafniense D-alanyl-(R)-lactate + ADP + phosphate
-
?
D-alanine + (R)-lactate + ATP
-
Desulfitobacterium hafniense Y51 D-alanyl-(R)-lactate + ADP + phosphate
-
?

Synonyms

Synonyms Comment Organism
D-Ala-D-Lac ligase
-
Desulfitobacterium hafniense
VanI
-
Desulfitobacterium hafniense

Cofactor

Cofactor Comment Organism Structure
ATP
-
Desulfitobacterium hafniense