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Literature summary for 6.1.1.6 extracted from

  • Kamenski, P.; Smirnova, E.; Kolesnikova, O.; Krasheninnikov, I.A.; Martin, R.P.; Entelis, N.; Tarassov, I.
    tRNA mitochondrial import in yeast: Mapping of the import determinants in the carrier protein, the precursor of mitochondrial lysyl-tRNA synthetase (2010), Mitochondrion, 10, 284-293.
    View publication on PubMed
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Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion cytosolic tRNAsLys tRK1 is partially targeted into mitochondria. Binding of tRK1 to the precursor of mitochondrial lysyl-tRNA synthetase preMsk1p, IIb class aminoacyl-tRNA synthetase, is a prerequisite of import. The hinge region of preMsk1p is essential to provide the import. The N-terminal domain of preMsk1p with the adjacent hinge region not only interacts with aminoacylated tRK1, but is also able to direct tRK1 import even in absence of the C-terminal domain. Enolase 2 participates as a putative RNA chaperone, suggesting that it may induce the import-active conformation in the tRNA Saccharomyces cerevisiae 5739
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Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
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Synonyms

Synonyms Comment Organism
tRK1
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 Saccharomyces cerevisiae