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Literature summary for 6.1.1.6 extracted from

  • Kawamata, H.; Magrane, J.; Kunst, C.; King, M.P.; Manfredi, G.
    Lysyl-tRNA synthetase is a target for mutant SOD1 toxicity in mitochondria (2008), J. Biol. Chem., 283, 28321-28328.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expressed in COS-7 cells, expressed in hSOD1 transgenic mice Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
Homo sapiens 5829
-
mitochondrion
-
Homo sapiens 5739
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
64000
-
predominantly as the 64 kDa processed form in the mitochondrial fraction, Western blot Homo sapiens
69000
-
unprocessed form (i.e. still containing the N-terminal mitochondrial targeting signal) in the cytosolic fraction, Western blot Homo sapiens
150000
-
mitoKARS, Western blot Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens Q15046
-
-

Subunits

Subunits Comment Organism
dimer
-
Homo sapiens

Synonyms

Synonyms Comment Organism
cytoKARS
-
Homo sapiens
KARS
-
Homo sapiens
Lysyl-tRNA synthetase
-
Homo sapiens
mitoKARS
-
Homo sapiens