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Literature summary for 6.1.1.5 extracted from

  • Kiener, A.; Rechsteiner, T.; Leisinger, T.
    Mutation to pseudomonic acid resistance of Methanobacterium thermoautotrophicum leads to an altered isoleucyl-tRNA synthetase (1986), FEMS Microbiol. Lett., 33, 15-18.
No PubMed abstract available
Search for more literature for 6.1.1.5

Protein Variants

Protein Variants Comment Organism
additional information pseudomonic acid-resistant mutant Methanothermobacter thermautotrophicus

Inhibitors

Inhibitors Comment Organism Structure
pseudomonic acid wild-type enzyme strongly inhibited, pseudomonic acid-resistant mutant only marginally Methanothermobacter thermautotrophicus

Organism

Organism UniProt Comment Textmining
Methanothermobacter thermautotrophicus
-
-
-
Methanothermobacter thermautotrophicus
-
 pseudomonic acid-resistant mutant
-
Methanothermobacter thermautotrophicus Marburg / DSM 2133
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-isoleucine + tRNAIle
-
 Methanothermobacter thermautotrophicus AMP + diphosphate + L-isoleucyl-tRNAIle
-
 ?
ATP + L-isoleucine + tRNAIle
-
 Methanothermobacter thermautotrophicus Marburg / DSM 2133 AMP + diphosphate + L-isoleucyl-tRNAIle
-
 ?