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Literature summary for 6.1.1.5 extracted from

  • Carr, A.C.; Igloi, G.L.; Penzer, G.R.; Plumbridge, J.A.
    The effect of spermine anf Mg2+ on the catalytic mechanism of isoleucine:tRNA ligase (1975), Eur. J. Biochem., 54, 169-173.
    View publication on PubMed
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Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ activates isoleucyl-tRNA formation Escherichia coli
Mg2+ synergistic effect with spermine Escherichia coli
Mg2+ enzyme-bound isoleucyl-AMP can be formed in the absence of Mg2+ and spermine Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
 K12
-
Escherichia coli
-
 B
-
Escherichia coli B / ATCC 11303
-
 B
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-isoleucine + tRNAIle
-
 Escherichia coli AMP + diphosphate + L-isoleucyl-tRNAIle
-
 ?
ATP + L-isoleucine + tRNAIle
-
 Escherichia coli B / ATCC 11303 AMP + diphosphate + L-isoleucyl-tRNAIle
-
 ?