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Literature summary for 6.1.1.5 extracted from

  • Xu, B.; Trawick, B.; Krudy, G.A.; Phillips, R.M.; Zhou.L.; Rosevear, P.R.
    Probing the metal binding sites of E. coli isoleucyl-tRNA synthetase (1994), Biochemistry, 33, 398-402.
    View publication on PubMed

Metals/Ions

Metals/Ions Comment Organism Structure
Zinc structural and catalytic role in aminoacylation Escherichia coli
Zinc 2 tightly bound zinc atoms per active site Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-isoleucine + tRNAIle
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Escherichia coli AMP + diphosphate + L-isoleucyl-tRNAIle
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additional information Ile + ATP + enzyme/Ile-AMP-enzyme + diphosphate, isoleucine-dependent ATP-diphosphate exchange Escherichia coli ?
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