Literature summary for 6.1.1.27 extracted from

Englert, M.; Moses, S.; Hohn, M.; Ling, J.; ODonoghue, P.; Soell, D.
Aminoacylation of tRNA 2'- or 3'-hydroxyl by phosphoseryl- and pyrrolysyl-tRNA synthetases (2013), FEBS Lett., 587, 3360-3364.

Search for more literature for 6.1.1.27

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + O-phospho-L-serine + tRNACys	Methanococcus maripaludis	the enzyme charges tRNACys with a 3'-deoxyadenosine, but not tRNACys without A76 or with a 2'-deoxyadensosine	AMP + diphosphate + O-phospho-L-seryl-tRNACys	-	?

Organism

Organism	UniProt	Comment	Textmining
Methanococcus maripaludis	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + O-phospho-L-serine + tRNACys	the enzyme charges tRNACys with a 3'-deoxyadenosine, but not tRNACys without A76 or with a 2'-deoxyadensosine	Methanococcus maripaludis	AMP + diphosphate + O-phospho-L-seryl-tRNACys	-	?

Synonyms

Synonyms	Comment	Organism
O-phosphoseryl-tRNA synthetase	-	Methanococcus maripaludis
SepRS	-	Methanococcus maripaludis

Cofactor

Cofactor	Comment	Organism	Structure
ATP	-	Methanococcus maripaludis

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Release 2023.1 (January 2023)