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Literature summary for 6.1.1.27 extracted from

  • Yuan, J.; Sheppard, K.; Soell, D.
    Amino acid modifications on tRNA (2008), Acta Biochim. Biophys. Sin. (Shanghai), 40, 539-553.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + O-phospho-L-serine + tRNACys Methanococcus maripaludis Methanococcus maripaludis encodes both the direct and indirect paths for Cys-tRNACys synthesis. SepS (encoding SepRS) can be deleted when the organism is grown in the presence of Cys AMP + diphosphate + O-phospho-L-seryl-tRNACys
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Organism

Organism UniProt Comment Textmining
Methanococcus maripaludis
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no activity in Methanobrevibacter smithii
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no activity in Methanosphaera stadtmanae
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + O-phospho-L-serine + tRNACys
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Methanococcus maripaludis AMP + diphosphate + O-phospho-L-seryl-tRNACys
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?
ATP + O-phospho-L-serine + tRNACys Methanococcus maripaludis encodes both the direct and indirect paths for Cys-tRNACys synthesis. SepS (encoding SepRS) can be deleted when the organism is grown in the presence of Cys Methanococcus maripaludis AMP + diphosphate + O-phospho-L-seryl-tRNACys
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?

Synonyms

Synonyms Comment Organism
SepRS
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Methanococcus maripaludis