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Literature summary for 6.1.1.26 extracted from

  • Lacey, V.; Louie, G.; Noel, J.; Wang, L.
    Expanding the library and substrate diversity of the pyrrolysyl-tRNA synthetase to incorporate unnatural amino acids containing conjugated rings (2013), ChemBioChem, 14, 2100-2105.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expressed in HeLa cells Methanosarcina mazei

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + L-pyrrolysine + tRNAPyl Methanosarcina mazei
-
AMP + diphosphate + L-pyrrolysyl-tRNAPyl
-
?

Organism

Organism UniProt Comment Textmining
Methanosarcina mazei
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-pyrrolysine + tRNAPyl
-
Methanosarcina mazei AMP + diphosphate + L-pyrrolysyl-tRNAPyl
-
?

Synonyms

Synonyms Comment Organism
PylRS
-
Methanosarcina mazei
pyrrolysyl-tRNA synthetase
-
Methanosarcina mazei

Cofactor

Cofactor Comment Organism Structure
ATP
-
Methanosarcina mazei