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Literature summary for 6.1.1.22 extracted from

  • Kron, M.A.; Wang, C.; Vodanovic-Jankovic, S.; Howard, O.M.; Kuhn, L.A.
    Interleukin-8-like activity in a filarial asparaginyl-tRNA synthetase (2012), Mol. Biochem. Parasitol., 185, 66-69.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + L-asparagine + tRNAAsn Brugia malayi
-
AMP + diphosphate + L-asparaginyl-tRNAAsn
-
?

Organism

Organism UniProt Comment Textmining
Brugia malayi
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-asparagine + tRNAAsn
-
Brugia malayi AMP + diphosphate + L-asparaginyl-tRNAAsn
-
?

Synonyms

Synonyms Comment Organism
AsnRS
-
Brugia malayi
Asparaginyl-tRNA synthetase
-
Brugia malayi

Cofactor

Cofactor Comment Organism Structure
ATP
-
Brugia malayi

General Information

General Information Comment Organism
physiological function the enzyme is a highly expressed excretory-secretory molecule which activates interleukin 8 (IL-8) receptors via extracellular domains that are different from those used by IL-8 Brugia malayi