Organism | UniProt | Comment | Textmining |
---|---|---|---|
Thermus thermophilus | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
AsnRS | - |
Thermus thermophilus |
Asparaginyl-tRNA synthetase | - |
Thermus thermophilus |
Organism | Comment | Expression |
---|---|---|
Thermus thermophilus | engineering of aspartyladenylate, AspAMP, specificity into asparaginyl-tRNA synthetase, AsnRS, whose substrate is asparaginyl-adenylate by CPD method, that uses a polar-hydrogen energy function for protein interactions and a coulomb/accessible surface area model for solvent effects, method development, overview. Application of an all-atom energy for protein interactions and a residue-pairwise generalized Born model for solvent effects, overview. The conformations and interactions are well maintained in molecular dynamics simulations and the sequences have an inverted specificity, favoring AspAMP over AsnAMP | additional information |