Literature summary for 6.1.1.21 extracted from

O'Hanlon, T.P.; Miller, F.W.
Genomic organization, transcriptional mapping, and evolutionary implications of the human bi-directional histidyl-tRNA synthetase locus (HARS/HARSL) (2002), Biochem. Biophys. Res. Commun., 294, 609-614.

Search for more literature for 6.1.1.21

Cloned(Commentary)

Cloned (Comment)	Organism
determination of DNA sequence, genomic organization, and chromosome mapping to 5q31.3	Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + L-histidine + tRNAHis	Homo sapiens	phylogenetic and evolutionary development	AMP + diphosphate + L-histidyl-tRNAHis	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P12081	-	-
Homo sapiens	P49590	histidyl-tRNA synthetase-like enzyme	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + L-histidine + tRNAHis	-	Homo sapiens	AMP + diphosphate + L-histidyl-tRNAHis	-	?
ATP + L-histidine + tRNAHis	phylogenetic and evolutionary development	Homo sapiens	AMP + diphosphate + L-histidyl-tRNAHis	-	?

Synonyms

Synonyms	Comment	Organism
HisRS	-	Homo sapiens
Histidine translase	-	Homo sapiens
histidine-tRNA ligase	-	Homo sapiens
histidine-tRNA ligase homolog	-	Homo sapiens
Histidyl-transfer ribonucleate synthetase	-	Homo sapiens
Histidyl-tRNA synthetase	-	Homo sapiens
Jo-1	-	Homo sapiens
Jo-1 antigen	-	Homo sapiens
Synthetase, histidyl-transfer ribonucleate	-	Homo sapiens

Cofactor

Cofactor	Comment	Organism	Structure
ATP	-	Homo sapiens

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Release 2023.1 (January 2023)