Literature summary for 6.1.1.20 extracted from

Kotik-Kogan, O.; Moor, N.; Tworowski, D.; Safro, M.
Structural basis for discrimination of L-phenylalanine from L-tyrosine by phenylalanyl-tRNA synthetase (2005), Structure, 13, 1799-1807.

Search for more literature for 6.1.1.20

Crystallization (Commentary)

Crystallization (Comment)	Organism
crystal structure of complexes of enzyme with L-Tyr, p-chlorophenylalanine, and L-tyrosyl-adenylate	Thermus thermophilus

Inhibitors

Inhibitors	Comment	Organism	Structure
L-phenylalanyl-5'-adenylate	-	Thermus thermophilus
L-Tyr	-	Thermus thermophilus
L-tyrosyl-adenylate	-	Thermus thermophilus

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.0018	-	L-Phe	-	Thermus thermophilus
0.13	-	ATP	-	Thermus thermophilus

Organism

Organism	UniProt	Comment	Textmining
Thermus thermophilus	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + L-Phe + tRNAPhe	-	Thermus thermophilus	AMP + diphosphate + L-phenylalanyl-tRNAPhe	-	?

Synonyms

Synonyms	Comment	Organism
PheRS	-	Thermus thermophilus

Ki Value [mM]

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
0.043	-	L-tyrosyl-adenylate	versus ATP	Thermus thermophilus
0.045	-	L-tyrosyl-adenylate	versus L-Phe	Thermus thermophilus
0.085	-	L-phenylalanyl-5'-adenylate	versus ATP	Thermus thermophilus
0.089	-	L-phenylalanyl-5'-adenylate	versus L-Phe	Thermus thermophilus
3.1	-	L-Tyr	versus L-Phe	Thermus thermophilus

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Release 2023.1 (January 2023)