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Literature summary for 6.1.1.20 extracted from

  • Vasil'eva, I.A.; Ankilova, V.N.; Lavrik, O.I.; Moor, N.A.
    Interaction of T. thermophilus phenylalanyl-tRNA synthetase with the 3'-terminal nucleotide of tRNAPhe (2000), Biochemistry, 65, 1157-1166.
    View publication on PubMed
Search for more literature for 6.1.1.20

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + L-phenylalanine + tRNAPhe Thermus thermophilus
-
 AMP + diphosphate + L-phenylalanyl-tRNAPhe
-
 ?

Organism

Organism UniProt Comment Textmining
Thermus thermophilus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-phenylalanine + tRNAPhe
-
 Thermus thermophilus AMP + diphosphate + L-phenylalanyl-tRNAPhe
-
 ?
ATP + L-phenylalanine + tRNAPhe wild-type tRNAPhe substrate, enzyme interacts with the 3'-end of tRNAPhe Thermus thermophilus AMP + diphosphate + L-phenylalanyl-tRNAPhe
-
 ?
ATP + L-phenylalanine + tRNAPhe-s6 G76 tRNAPhe variant, 370fold reduced activity compared to wild-type tRNAPhe Thermus thermophilus AMP + diphosphate + L-phenylalanyl-tRNAPhe-s6 G76
-
 ?
additional information no activity with tRNAPhe-s4 U76, a tRNA variant harboring a 4-thiouridine residue in the 3'-end Thermus thermophilus ?
-
 ?

Subunits

Subunits Comment Organism
More alphabeta organization, the alpha-subunit is the catalytically active one Thermus thermophilus

Synonyms

Synonyms Comment Organism
CML33
-
 Thermus thermophilus
FRS
-
 Thermus thermophilus
HSPC173
-
 Thermus thermophilus
L-Phenylalanyl-tRNA synthetase
-
 Thermus thermophilus
Phenylalanine translase
-
 Thermus thermophilus
Phenylalanine--tRNA ligase
-
 Thermus thermophilus
Phenylalanine-tRNA synthetase
-
 Thermus thermophilus
Phenylalanyl transfer ribonucleic acid synthetase
-
 Thermus thermophilus
Phenylalanyl-transfer ribonucleate synthetase
-
 Thermus thermophilus
Phenylalanyl-transfer RNA ligase
-
 Thermus thermophilus
Phenylalanyl-transfer RNA synthetase
-
 Thermus thermophilus
Phenylalanyl-tRNA ligase
-
 Thermus thermophilus
Phenylalanyl-tRNA synthetase
-
 Thermus thermophilus
PheRS
-
 Thermus thermophilus
Synthetase, phenylalanyl-transfer ribonucleate
-
 Thermus thermophilus

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Thermus thermophilus