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Literature summary for 6.1.1.19 extracted from

  • Freist, W.; Sternbach, H.; von der Haar, F.; Cramer, F.
    Threonyl-tRNA, lysyl-tRNA and arginyl-tRNA synthetases from baker's yeast. Substrate specificity with regard to ATP analogues (1978), Eur. J. Biochem., 84, 499-502.
    View publication on PubMed
Search for more literature for 6.1.1.19

Inhibitors

Inhibitors Comment Organism Structure
3'-Deoxyadenosine 5'-triphosphate
-
 Saccharomyces pastorianus
8-bromoadenosine 5'-triphosphate
-
 Saccharomyces pastorianus
purine-riboside 5'-triphosphate
-
 Saccharomyces pastorianus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.2
-
 tubercidin 5'-triphosphate formycin 5'-triphosphate, 2'-deoxyadenosine 5'-triphosphate, 3'-O-methyladenosine 5'-triphosphate Saccharomyces pastorianus
0.3
-
 ATP 2'-O-methyladenosine 5'-triphosphate Saccharomyces pastorianus

Organism

Organism UniProt Comment Textmining
Saccharomyces pastorianus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2'-deoxyadenosine 5'-triphosphate + L-arginine + tRNAArg
-
 Saccharomyces pastorianus 2'-deoxyadenosine 5'-monophosphate + diphosphate + L-arginyl-tRNAArg
-
 ?
2'-O-methyladenosine 5'-triphosphate + L-arginine + tRNAArg
-
 Saccharomyces pastorianus 2'-O-methyladenosine 5'-monophosphate + diphosphate + L-arginyl-tRNAArg
-
 ?
3'-O-methyladenosine 5'-triphosphate + L-arginine + tRNAArg
-
 Saccharomyces pastorianus 3'-O-methyladenosine 5'-monophosphate + diphosphate + L-arginyl-tRNAArg
-
 ?
ATP + L-arginine + tRNAArg
-
 Saccharomyces pastorianus AMP + diphosphate + L-arginyl-tRNAArg
-
 ?
formycin 5'-triphosphate + L-arginine + tRNAArg
-
 Saccharomyces pastorianus formycin 5'-monophosphate + diphosphate + L-arginyl-tRNAArg
-
 ?
additional information positions 2, 6, 7, 8, and 9 of the purine moiety and 2' and 3' of the sugar moiety of the ATP molecule are important for catalytic action of the aminoacyl-tRNA synthetase Saccharomyces pastorianus ?
-
 ?
tubercidin 5'-triphosphate + L-arginine + tRNAArg
-
 Saccharomyces pastorianus tubercidin 5'-monophosphate + diphosphate + L-arginyl-tRNAArg
-
 ?