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Literature summary for 6.1.1.15 extracted from

  • Jain, V.; Kikuchi, H.; Oshima, Y.; Sharma, A.; Yogavel, M.
    Structural and functional analysis of the anti-malarial drug target prolyl-tRNA synthetase (2014), J. Struct. Funct. Genomics, 15, 181-190 .
    View publication on PubMed
Search for more literature for 6.1.1.15

Crystallization (Commentary)

Crystallization (Comment) Organism
-
 Plasmodium falciparum

Inhibitors

Inhibitors Comment Organism Structure
halofuginone
-
 Plasmodium falciparum

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
 Plasmodium falciparum 5737
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + L-proline + tRNAPro Plasmodium falciparum
-
 AMP + diphosphate + L-prolyl-tRNAPro
-
 ?

Organism

Organism UniProt Comment Textmining
Plasmodium falciparum Q8I5R7
-
-

Purification (Commentary)

Purification (Comment) Organism
amylose bead column chromatography, heparin column chromatography, and Superdex 200 gel filtration Plasmodium falciparum

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-proline + tRNAPro
-
 Plasmodium falciparum AMP + diphosphate + L-prolyl-tRNAPro
-
 ?

Subunits

Subunits Comment Organism
? x * 58000, SDS-PAGE Plasmodium falciparum

Synonyms

Synonyms Comment Organism
Prolyl-tRNA synthetase
-
 Plasmodium falciparum
PRS
-
 Plasmodium falciparum

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
50
-
 melting temperature of the apoprotein Plasmodium falciparum

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Plasmodium falciparum