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Literature summary for 6.1.1.14 extracted from
- Functional substitution of a eukaryotic glycyl-tRNA synthetase with an evolutionarily unrelated bacterial cognate enzyme (2014), PLoS ONE, 9, e94659 .
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Saccharomyces cerevisiae grs1-deficient cells | Thermus thermophilus |
| expressed in Saccharomyces cerevisiae grs1-deficient cells | Homo sapiens |
| expressed in Saccharomyces cerevisiae grs1-deficient cells | Arabidopsis thaliana |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytoplasm | - |
Thermus thermophilus | 5737 | - |
| cytoplasm | - |
Homo sapiens | 5737 | - |
| cytoplasm | - |
Saccharomyces cerevisiae | 5737 | - |
| cytoplasm | - |
Arabidopsis thaliana | 5737 | - |
| mitochondrion | - |
Homo sapiens | 5739 | - |
| mitochondrion | - |
Saccharomyces cerevisiae | 5739 | - |
| mitochondrion | - |
Arabidopsis thaliana | 5739 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + glycine + tRNAGly | Thermus thermophilus | - |
AMP + diphosphate + glycyl-tRNAGly | - |
? |  |
| ATP + glycine + tRNAGly | Homo sapiens | - |
AMP + diphosphate + glycyl-tRNAGly | - |
? | |
| ATP + glycine + tRNAGly | Saccharomyces cerevisiae | - |
AMP + diphosphate + glycyl-tRNAGly | - |
? | |
| ATP + glycine + tRNAGly | Arabidopsis thaliana | - |
AMP + diphosphate + glycyl-tRNAGly | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Arabidopsis thaliana | - |
- |
- |
| Homo sapiens | - |
- |
- |
| Saccharomyces cerevisiae | - |
- |
- |
| Thermus thermophilus | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + glycine + tRNAGly | - |
Thermus thermophilus | AMP + diphosphate + glycyl-tRNAGly | - |
? | |
| ATP + glycine + tRNAGly | - |
Homo sapiens | AMP + diphosphate + glycyl-tRNAGly | - |
? | |
| ATP + glycine + tRNAGly | - |
Saccharomyces cerevisiae | AMP + diphosphate + glycyl-tRNAGly | - |
? | |
| ATP + glycine + tRNAGly | - |
Arabidopsis thaliana | AMP + diphosphate + glycyl-tRNAGly | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| GARS | - |
Thermus thermophilus |
| GARS | - |
Homo sapiens |
| GARS | - |
Arabidopsis thaliana |
| Glycyl-tRNA synthetase | - |
Thermus thermophilus |
| Glycyl-tRNA synthetase | - |
Homo sapiens |
| Glycyl-tRNA synthetase | - |
Saccharomyces cerevisiae |
| Glycyl-tRNA synthetase | - |
Arabidopsis thaliana |
| GlyRS | - |
Thermus thermophilus |
| GlyRS | - |
Homo sapiens |
| GlyRS | - |
Saccharomyces cerevisiae |
| GlyRS | - |
Arabidopsis thaliana |
| GRS1 | - |
Thermus thermophilus |
| GRS1 | - |
Homo sapiens |
| GRS1 | - |
Saccharomyces cerevisiae |
| GRS1 | - |
Arabidopsis thaliana |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| ATP | - |
Thermus thermophilus | |
| ATP | - |
Homo sapiens | |
| ATP | - |
Saccharomyces cerevisiae | |
| ATP | - |
Arabidopsis thaliana | |
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Release 2023.1 (January 2023)
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