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Literature summary for 6.1.1.11 extracted from

  • Foerster, C.; Brauer, A.B.; Fuerste, J.P.; Betzel, C.h.; Weber, M.; Cordes, F.; Erdmann, V.A.
    Superposition of a tRNASer acceptor stem microhelix into the seryl-tRNA synthetase complex (2007), Biochem. Biophys. Res. Commun., 362, 415-418.
    View publication on PubMed

Crystallization (Commentary)

Crystallization (Comment) Organism
tRNASer-seryl-tRNA synthetase complex, X-ray diffraction structure determination and analysis at 2.9 A resolution, the 1.8 A-resolution tRNASer acceptor stem crystal structure is superimposed to a 2.9 A-resolution crystal structure of a tRNASer-seryl-tRNA synthetase complex for a visualization of the binding environment of the tRNASer microhelix, modeling Thermus thermophilus

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+
-
Thermus thermophilus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + L-serine + tRNASer Thermus thermophilus
-
AMP + diphosphate + L-seryl-tRNASer
-
?

Organism

Organism UniProt Comment Textmining
Thermus thermophilus P34945
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-serine + tRNASer
-
Thermus thermophilus AMP + diphosphate + L-seryl-tRNASer
-
?
ATP + L-serine + tRNASer a two-step reaction, seryl-tRNA synthetase is a class II synthetase depending on rather few and simple identity elements in tRNASer to determine the amino acid specificity, tRNASer acceptor stem microhelices can be aminoacylated with serine as part of the tRNA a valuable tool for investigating the structural motifs in a tRNASer-seryl-tRNA synthetase complex, tRNASer secondary structure, overview Thermus thermophilus AMP + diphosphate + L-seryl-tRNASer
-
?

Synonyms

Synonyms Comment Organism
SerRS
-
Thermus thermophilus
Seryl-tRNA synthetase
-
Thermus thermophilus

Cofactor

Cofactor Comment Organism Structure
ATP
-
Thermus thermophilus