Cloned (Comment) | Organism |
---|---|
MetRS, phylogenetic analysis, the viral aminoacyl tRNA synthetases have not been acquired recently by horizontal gene transfer from a cellular host but rather militate in favor of an intricate evolutionary relationship between large DNA viruses and ancestral eukaryotes | Acanthamoeba polyphaga Mimivirus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | kinetics with Escherichia coli native tRNAMet and initiator tRNAMet, and Saccharomyces cerevisiae native tRNAMet and initiator tRNAMet, overview | Acanthamoeba polyphaga Mimivirus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | - |
Acanthamoeba polyphaga Mimivirus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + L-methionine + tRNAMet | Acanthamoeba polyphaga Mimivirus | the MetRS specificity for methionine and conformity with the identity rules for tRNAMet for archea/eukarya, anticodon binding site, overview | AMP + diphosphate + L-methionyl-tRNAMet | - |
? | |
additional information | Acanthamoeba polyphaga Mimivirus | mimivirus aminoacyl-tRNA synthetases function as regular translation enzymes in infected amoebas | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Acanthamoeba polyphaga Mimivirus | - |
- |
- |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
activity with Escherichia coli native tRNAMet and initiator tRNAMet, and Saccharomyces cerevisiae native tRNAMet and initiator tRNAMet, overview | Acanthamoeba polyphaga Mimivirus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + L-methionine + tRNAMet | the MetRS specificity for methionine and conformity with the identity rules for tRNAMet for archea/eukarya, anticodon binding site, overview | Acanthamoeba polyphaga Mimivirus | AMP + diphosphate + L-methionyl-tRNAMet | - |
? | |
ATP + L-methionine + tRNAMet | functional idiosyncrasies of the viral MetRS, activity with Escherichia coli native tRNAMet and initiator tRNAMet, and Saccharomyces cerevisiae native tRNAMet and initiator tRNAMet, overview, the MetRS specificity for methionine and recognition of the tRNAMet acceptor stem show conformity with the identity rules for tRNAMet for archea/eukarya, overview | Acanthamoeba polyphaga Mimivirus | AMP + diphosphate + L-methionyl-tRNAMet | - |
? | |
additional information | mimivirus aminoacyl-tRNA synthetases function as regular translation enzymes in infected amoebas | Acanthamoeba polyphaga Mimivirus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
methionyl-tRNA synthetase | - |
Acanthamoeba polyphaga Mimivirus |
MetRS | - |
Acanthamoeba polyphaga Mimivirus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
30 | - |
assay at | Acanthamoeba polyphaga Mimivirus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
assay at | Acanthamoeba polyphaga Mimivirus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Acanthamoeba polyphaga Mimivirus |