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Literature summary for 6.1.1.10 extracted from

  • Posorske, L.H.; Cohn, M.; Yanagisawa, N.; Auld, D.S.
    Methionyl-tRNA synthetase of Escherichia coli. A zinc metalloprotein (1979), Biochim. Biophys. Acta, 576, 128-133.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
1,10-phenanthroline little or no inhibition by 1,7-phenanthroline and 4,7-phenanthroline Escherichia coli
2,2'-dipyridyl
-
Escherichia coli
NH4+ ATP-diphosphate exchange Escherichia coli

Metals/Ions

Metals/Ions Comment Organism Structure
Mn2+ enzyme binds 2 Mn2+ per dimer, no binding with the trypsin-modified monomer Escherichia coli
Zn2+ contains two zinc atoms per dimer, one per subunit Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-methionine + tRNAMet
-
Escherichia coli AMP + diphosphate + L-methionyl-tRNAMet
-
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