Literature summary for 5.6.2.2 extracted from

Mizushina, Y.; Kasai, N.; Sugawara, F.; Iida, A.; Yoshida, H.; Sakaguchi, K.
Three-dimensional structural model analysis of the binding site of lithocholic acid, an inhibitor of DNA polymerase beta and DNA topoisomerase II (2001), J. Biochem., 130, 657-664.

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Inhibitors

Inhibitors	Comment	Organism	Structure
lithocholic acid	IC50: 0.015 mM, the lithocholic interaction interface has a pocket comprised of three amino acids, Lys720, Leu760 and Thr791	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

IC50 Value

IC50 Value	IC50 Value Maximum	Comment	Organism	Inhibitor	Structure
0.015	-	IC50: 0.015 mM, the lithocholic interaction interface has a pocket comprised of three amino acids, Lys720, Leu760 and Thr791	Homo sapiens	lithocholic acid

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Release 2023.1 (January 2023)