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Literature summary for 5.6.2.2 extracted from

  • Lindsley, J.E.; Wang, J.C.
    On the coupling between ATP usage and DNA transport by yeast DNA topoisomerase II (1993), J. Biol. Chem., 268, 8096-8104.
    View publication on PubMed
Search for more literature for 5.6.2.2

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
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Reaction

Reaction Comment Organism Reaction ID
ATP-dependent breakage, passage and rejoining of double-stranded DNA model in which the DNA-bound enzyme acts as an ATP-operated clamp for the capture and transport of a second DNA segment Saccharomyces cerevisiae
a

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
network of DNA rings + ATP + H2O decatenation Saccharomyces cerevisiae monomeric DNA circles + ADP + phosphate
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supercoiled DNA + ATP + H2O catenation Saccharomyces cerevisiae catenated DNA networks + ADP + phosphate
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supercoiled DNA + ATP + H2O relaxation Saccharomyces cerevisiae relaxed DNA + ADP + phosphate
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supercoiled DNA + ATP + H2O relaxation of negatively supercoiled DNA Saccharomyces cerevisiae relaxed DNA + ADP + phosphate
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