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Literature summary for 5.6.2.2 extracted from
- Purification and properties of type II DNA topoisomerase from embryos of Drosophila melanogaster (1983), Methods Enzymol., 100, 161-170.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Drosophila melanogaster | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Drosophila melanogaster |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| embryo | - |
Drosophila melanogaster | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
- |
Drosophila melanogaster |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | the enzyme can alter the linking number of DNA only in steps of two | Drosophila melanogaster | ? | - |
? |  |
| additional information | at high concentrations the enzyme can knot circular duplex DNA molecules | Drosophila melanogaster | ? | - |
? | |
| network of DNA rings + ATP + H2O | decatenation | Drosophila melanogaster | monomeric DNA circles + ADP + phosphate | - |
? | |
| supercoiled DNA + ATP + H2O | catenation | Drosophila melanogaster | catenated DNA networks + ADP + phosphate | - |
? | |
| supercoiled DNA + ATP + H2O | relaxation | Drosophila melanogaster | relaxed DNA + ADP + phosphate | - |
? | |
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