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Literature summary for 5.6.2.2 extracted from

  • Andersen, A.H.; Bendixen, C.; Westergaard, O.
    DNA topoisomerases (1996), DNA Replication in eucaryotic cells, Cold Spring Harbor Laboratory Press, , 587-617.
No PubMed abstract available
Search for more literature for 5.6.2.2

Crystallization (Commentary)

Crystallization (Comment) Organism
determination of crystal structure of fragments eukaryota

Inhibitors

Inhibitors Comment Organism Structure
2-Nitroimidazoles
-
 eukaryota
9-Hydroxy-isoellipticine
-
 eukaryota
Aclarubicin
-
 eukaryota
Acridines
-
 eukaryota
adriamycin
-
 eukaryota
Epipodophyllotoxins
-
 eukaryota
genistein
-
 eukaryota
Merbarone
-
 eukaryota
Mitoxantrone
-
 eukaryota
quinolones
-
 eukaryota
suramin
-
 eukaryota

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information eukaryota involvement in RNA polymerase II transcription ?
-
 ?

Organism

Organism UniProt Comment Textmining
Bacteria
-
-
-
eukaryota
-
-
-
Homo sapiens
-
-
-
Mus musculus
-
-
-
Saccharomyces cerevisiae
-
-
-

Reaction

Reaction Comment Organism Reaction ID
ATP-dependent breakage, passage and rejoining of double-stranded DNA mechanistic studies eukaryota
a

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information involvement in RNA polymerase II transcription eukaryota ?
-
 ?
network of DNA rings + ATP + H2O decatenation Bacteria monomeric DNA circles + ADP + phosphate
-
 ?
network of DNA rings + ATP + H2O decatenation eukaryota monomeric DNA circles + ADP + phosphate
-
 ?
network of DNA rings + ATP + H2O decatenation Mus musculus monomeric DNA circles + ADP + phosphate
-
 ?
network of DNA rings + ATP + H2O decatenation Homo sapiens monomeric DNA circles + ADP + phosphate
-
 ?
network of DNA rings + ATP + H2O decatenation Saccharomyces cerevisiae monomeric DNA circles + ADP + phosphate
-
 ?
supercoiled DNA + ATP + H2O catenation Bacteria catenated DNA networks + ADP + phosphate
-
 ?
supercoiled DNA + ATP + H2O catenation eukaryota catenated DNA networks + ADP + phosphate
-
 ?
supercoiled DNA + ATP + H2O catenation Mus musculus catenated DNA networks + ADP + phosphate
-
 ?
supercoiled DNA + ATP + H2O catenation Homo sapiens catenated DNA networks + ADP + phosphate
-
 ?
supercoiled DNA + ATP + H2O catenation Saccharomyces cerevisiae catenated DNA networks + ADP + phosphate
-
 ?
supercoiled DNA + ATP + H2O relaxation Bacteria relaxed DNA + ADP + phosphate
-
 ?
supercoiled DNA + ATP + H2O relaxation eukaryota relaxed DNA + ADP + phosphate
-
 ?
supercoiled DNA + ATP + H2O relaxation Mus musculus relaxed DNA + ADP + phosphate
-
 ?
supercoiled DNA + ATP + H2O relaxation Homo sapiens relaxed DNA + ADP + phosphate
-
 ?
supercoiled DNA + ATP + H2O relaxation Saccharomyces cerevisiae relaxed DNA + ADP + phosphate
-
 ?
supercoiled DNA + ATP + H2O relaxation of negatively or positively supercoiled DNA Bacteria relaxed DNA + ADP + phosphate
-
 ?
supercoiled DNA + ATP + H2O relaxation of negatively or positively supercoiled DNA eukaryota relaxed DNA + ADP + phosphate
-
 ?
supercoiled DNA + ATP + H2O relaxation of negatively or positively supercoiled DNA Saccharomyces cerevisiae relaxed DNA + ADP + phosphate
-
 ?