Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 5.6.2.1 extracted from

  • Chan, M.K.; Lim, S.K.; Miswan, N.; Chew, A.L.; Noordin, R.; Khoo, B.Y.
    Expression of stable and active human DNA topoisomerase I in Pichia pastoris (2018), Protein Expr. Purif., 141, 52-62 .
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Pichia pastoris strains X33, GS115, SMD1168H and KM71H Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
camptothecin
-
Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
MDA-MB-231 cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
supercoiled pBR322 plasmid DNA
-
Homo sapiens relaxed pBR322 plasmid DNA
-
?

Synonyms

Synonyms Comment Organism
DNA topoisomerase I
-
Homo sapiens
topoI
-
Homo sapiens