Inhibitors | Comment | Organism | Structure |
---|---|---|---|
camptothecin | - |
Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
chromosome | - |
Homo sapiens | 5694 | - |
nucleus | - |
Homo sapiens | 5634 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
UML-49 cell | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
Topoisomerase I | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
additional information | inhibition of topoisomerase I prevents chromosome breakage at common fragile sites. Polymerase-helicase uncoupling is a key initial event in this process | Homo sapiens |