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Literature summary for 5.6.2.1 extracted from

  • Han, H.J.; Tan, N.H.; Zeng, G.Z.; Fan, J.T.; Huang, H.Q.; Ji, C.J.; Jia, R.R.; Zhao, Q.S.; Zhang, Y.J.; Hao, X.J.; Wang, L.Q.
    Natural inhibitors of DNA topoisomerase I with cytotoxicities (2008), Chem. Biodivers., 5, 1364-1368.
    View publication on PubMed
Search for more literature for 5.6.2.1

Application

Application Comment Organism
drug development topo-I inhibitors as new anticancer drugs Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
(-)-cryptotanshinone diterpenoid from Salvia castanea f. tomentos Homo sapiens
10-Hydroxycamptothecin
-
 Homo sapiens
7-ketoroyleanone diterpenoid from Orthosiphon wulfenioides Homo sapiens
antofine alkaloid from Cynanchum komarovii Homo sapiens
camptothecin
-
 Homo sapiens
chrysin 6-C-beta-D-glucopyranosyl 8-C-alpha-L-arabinopyranoside flavonoid from Scutellaria amoena Homo sapiens
cis-2',5,7-trihydroxyflavanonol 3-O-beta-D-glucopyranoside flavonoid from Scutellaria amoena Homo sapiens
dihydrotanshinone I diterpenoid from Salvia castanea f. tomentos Homo sapiens
taxol
-
 Homo sapiens
vincristine
-
 Homo sapiens
winchic acid triterpenoid from Winchia calophylla Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
A-549 cell
-
 Homo sapiens
-
BEL-7402 cell
-
 Homo sapiens
-
BGC-823 cell
-
 Homo sapiens
-
DU-145 cell
-
 Homo sapiens
-
HT-29 cell
-
 Homo sapiens
-
MCF-7 cell
-
 Homo sapiens
-
MDA-MB-231 cell
-
 Homo sapiens
-
SGC-7901 cell
-
 Homo sapiens
-
U-251 MG cell
-
 Homo sapiens
-

Synonyms

Synonyms Comment Organism
DNA topoisomerase I
-
 Homo sapiens
Topo I
-
 Homo sapiens