Literature summary for 5.6.2.1 extracted from

Christmann-Franck, S.; Fermandjian, S.; Mirambeau, G.; Der Garabedian, P.A.
Molecular modelling studies on the interactions of human DNA topoisomerase IB with pyridoxal-compounds (2007), Biochimie, 89, 468-473.

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Protein Variants

Protein Variants	Comment	Organism
additional information	molecular models of human topoisomerase I bearing K532-PL, K532-PLP and K532-PLP-AMP modified residues build with the molecular modelling package Insight II	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
additional information	Inhibition: PL	Homo sapiens
pyridoxal	-	Homo sapiens
pyridoxal 5'-diphospho-5'-adenosine	-	Homo sapiens
pyridoxal 5'-phosphate	competitive inhibitor of Candida guilliermondii topoisomerase I	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P11387	-	-

Synonyms

Synonyms	Comment	Organism
topoisomerase IB	-	Homo sapiens

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Release 2023.1 (January 2023)